AoU Research Priorities Use Cases

Can pollen allergies be isolated by genetics, confirmed by allergy testing, and exposure be tracked to limit asthma attacks?

A cohort of asthma patients (who believe they have a pollen allergy) would undergo genetic testing to identify genetic markers. Those patients would undergo blood and skin allergy testing to confirm the allergy, and then the patients would be utilize a mobile monitor to track the weather and environmental exposures (esp. pollen) that are causal to asthma incidences. With a more complete picture of pollen allergen impacts on patients they would be able to limit the negative health outcomes.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Continuous monitoring

If Data Item #2 was not in the dropdown, please enter it here. Asthma Exacerbations (flare-ups/attacks)

Method #2

Specification #2 At specified times anchored to the clinical event

If Data Item #3 was not in the dropdown, please enter it here allergy testing

Method #3

If Method #3 was not in the dropdown, please enter it here Skin Allergy Test

Specification #3 Once

If Specification #3 was not in the dropdown, please enter it here child, teenager, early adult, adult, elderly

Data Item #4 Genome

Method #4 Whole Exomic Sequencing (WES)

Specification #4 Mobile monitors would be used continuously for one week duration at 1 month, 6 months, and 1 year after injury

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Idea No. 47