AoU Research Priorities Use Cases

Can the recycling of influenza viruses explain changes in phenotypes of CHD cases?

I proposed that the 1950s-60s CHD deaths were associated with H1-H2 Influenza A re-infectiosn of H3 Influenza primed individuals (born around 1890). After 1968, when the H3 influenza virus returned, high serum cholesterol CHD cases declined and a second atherogenic phenotype emerged (H3 re-infection of H1-primed cohorts born after 1900 and more after 1918?). Would CHD mortality with high serum cholesterol levels increase again as cohorts born after 1968 (H3) become re-infected with H1 viruses?



1 vote
Idea No. 684