AoU Research Priorities Use Cases

Can we identify risk factors for Age Related Macular Degeneration (AMD) ?

From NEI Working Group on AMD

Use cohort with structural and functional phenotyping with genetic and EHRs to identify risk factors, and their interactive effects, for AMD development/progression. A subset could be identified based on AMD or family history of AMD (via EHRs), or presence of high-risk variants (via WGS), and could then be followed annually with fundus autofluorescence, OCT, dark adaptation. Additional data to collect would include AMD risk factors (hypertension, obesity, etc.)



16 votes
Idea No. 308