AoU Research Priorities Use Cases

Conduct research to understand the pathogenesis of Lipedema so as to differentiate between Obesity and Lymphedema.

Lipedema is an underdiagnosed or misdiagnosed Adipose Disorder that is often mistaken for Obesity or Lymphedema. It is estimated that 1 out of 9 adult females suffer from this fat disorder that is marked by an abnormal deposition of fat in the lower body that is resistant to diet and exercise. Research into the pathogenesis of Lipedema would lead to better diagnostic methods and treatment modalities. Genetics are thought to play a role as is estrogen and inflammation of SAT.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. History, health

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Physical exam

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Quarterly

Data Item #2 O-estradiol

Method #2 Blood test

Specification #2 Quarterly



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Idea No. 845