AoU Research Priorities Use Cases

Cytochrome P450 polymorphisms affect patient metabolism; would profiling CYP in large studies help predict patient outcomes?

Establish CYP profiling as a standard part of data collection in all large studies, especially related to pain management, immunology, cardiovascular dysfunction, pharmacology. Based upon existing research, it can be anticipated that CYP profiles and polymorphism data may partition certain studies' patient populations into groups with common outcomes (negative, positive, neutral.) Regarding the opioid crisis alone, CYP awareness is of national importance, and can improve treatment/outcomes.

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Idea No. 104