AoU Research Priorities Use Cases

Cytochrome P450 polymorphisms affect patient metabolism; would profiling CYP in large studies help predict patient outcomes?

Establish CYP profiling as a standard part of data collection in all large studies, especially related to pain management, immunology, cardiovascular dysfunction, pharmacology. Based upon existing research, it can be anticipated that CYP profiles and polymorphism data may partition certain studies' patient populations into groups with common outcomes (negative, positive, neutral.) Regarding the opioid crisis alone, CYP awareness is of national importance, and can improve treatment/outcomes.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. Cytochrome p450 phenotyping

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Blood test

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Once

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Idea No. 104