AoU Research Priorities Use Cases

Differentiating healthy neurological aging from incipient nervous system dysfunction using smartphone apps.

Neurons are mostly non-renewing cells and neurodegenerative diseases are often diagnosed after many already died. This severely limits therapeutic efficacy. We propose accurate, convenient measures of broad neurological functions using developed smartphone apps to test whether derived subject-specific progression slopes can differentiate healthy aging from incipient neurological dysfunction. Such analysis may eventually serve as personalized results in clinical trials and broad medical practice.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

If you did not find your method for obtaining Data Item #1 in the dropdown selection above, please enter it here. We have developed an interactive smartphone app on Android platform that measures (in approximately 15-20 minutes) motoric, sensory and cognitive functions. We have tested that the app can differentiate healthy people from subjects with neurological diseases, such as multiple sclerosis.

If you did not find your methodology specifications for Data Item #1 above, please enter it here. Smartphone Test Suite App

If Data Item #2 was not in the dropdown, please enter it here. Sensor data for lower extremity tests where Bluetooth sensors worn on ankle straps can monitor gait, single leg raise, or repeated lower extremity movements.

If Method #2 was not in the dropdown, please enter it here Smartphone Test Suite App

If Specification #2 was not in the dropdown, please enter it here: Once every month


24 votes
Idea No. 365