AoU Research Priorities Use Cases

Do exposures to endocrine active compounds during puberty increase breast cancer risk?

Emerging data suggest that exposure to toxicants during key life stages, such as puberty, alter breast development and influence cancer risk. A comprehensive measure of environmental exposures (e.g. air pollutants, parabens, phenols, pesticides) at puberty could link to future breast cancer associated diagnoses (benign breast disease, atypical ductal hyperplasia, ductal carcinoma in situ, invasive breast cancer) identified through electronic health records.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. Environmental exposure

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Biochemical assay

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Once per year

Data Item #2 Clinical outcomes

Method #2 Electronic Health Records (EHR)

Specification #2 Continuous monitoring


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Idea No. 644