AoU Research Priorities Use Cases

Do exposures to endocrine active compounds during puberty increase breast cancer risk?

Emerging data suggest that exposure to toxicants during key life stages, such as puberty, alter breast development and influence cancer risk. A comprehensive measure of environmental exposures (e.g. air pollutants, parabens, phenols, pesticides) at puberty could link to future breast cancer associated diagnoses (benign breast disease, atypical ductal hyperplasia, ductal carcinoma in situ, invasive breast cancer) identified through electronic health records.

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Idea No. 644