AoU Research Priorities Use Cases

Do specific diabetes drugs increase the risk of peripheral artery disease, a diabetic foot ulcer or an amputation?

A major advance in diabetes treatment is the finding that specific glucose-lowering drugs reduce the risk of cardiovascular disease. The results were tempered by the increased risk of amputations for the groups that received the SGLT2 inhibitor, canagliflozin. The generalizability of this finding is unknown. An understanding of the association of specific diabetes drugs with lower extremity complications will allow a better assessment of the risks and benefits for individual patients.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. History, medication

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Electronic Health Records (EHR)

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Quarterly

If Data Item #2 was not in the dropdown, please enter it here. diabetic foot ulcer

Method #2 Electronic Health Records (EHR)

Specification #2 Quarterly

If Data Item #3 was not in the dropdown, please enter it here peripheral artery disease

Method #3 Electronic Health Records (EHR)

Specification #3 Quarterly

If Data Item #4 was not in the dropdown, please enter it here amputation

Method #4 Procedure codes

Specification #4 Quarterly

Data Item #5 Hemoglobin A1C (HbA1C)

Method #5 Electronic Health Records (EHR)

Specification #5 Quarterly

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Idea No. 458