AoU Research Priorities Use Cases

Does data from deep sequencing tumors (personalized medicine) allow for targeted treatment and better survival of patients?

1. Divide "cancer" into multiple classes (ie breast, lung, pancreatic, etc.) and sequence tumors from 50-100 patients undergoing treatment. As with breast cancer, identify markers aligning with specific treatments and outcomes.

2. Perform the "clinical" trial. Use the deep sequencing as a diagnostic to aid in planning the treatment for a set of 50-100 patients for a given type of cancer. Track the outcomes: survival time, length of remission, effectiveness of treatment, etc. Use data to revise.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. RNA-seq data on high throughput platform (ie Illumina)

If you did not find your method for obtaining Data Item #1 in the dropdown selection above, please enter it here. Biopsy

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. At specified times anchored to the clinical event

Data Item #2 Clinical outcomes

Method #2 Physical exam

Specification #2 At specified times anchored to the clinical event

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Idea No. 150