AoU Research Priorities Use Cases

Does midurethral sling surgery (MuSS) for stress urinary incontinence (SUI) improve metabolic risk profile?

SUI may contribute to reduced physical activity and poorer adherence to diuretics, thereby increasing metabolic risk profile. This study will identify a prospective subcohort of women aged 18+ with incident MuSS to compare metabolic risk profile before and after successful surgery. We hypothesize successful MuSS will decrease need to urinate during day, increase level of physical activity, and reduce metabolic risk. Patient perceived surgical outcome will serve as a proxy for success of MuSS.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. Midurethral sling surgery

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Electronic Health Records (EHR)

If you did not find your methodology specifications for Data Item #1 above, please enter it here. Procedure codes

If Data Item #2 was not in the dropdown, please enter it here. Metabolic Risk Profile (fasting high-density lipoprotein, fasting triglycerides, and fasting blood glucose or HA1C, blood pressure, BMI and waist circumference)

Method #2 Electronic Health Records (EHR)

If Specification #2 was not in the dropdown, please enter it here: collected at baseline and 1 year following surgery

If Data Item #3 was not in the dropdown, please enter it here Number of daytime urinations

Method #3 Survey

If Specification #3 was not in the dropdown, please enter it here bladder diary collected on the cohort who underwent the MUS. Instructions could be mailed to participants

If Data Item #4 was not in the dropdown, please enter it here Patient perceived surgery outcome

Method #4 Survey

If Specification #4 was not in the dropdown, please enter it here Validated survey question, e.g., Patient Global Impression of Change Scale (PGIC)

If Data Item #5 was not in the dropdown, please enter it here Physical activity level

Method #5

If Specification #5 was not in the dropdown, please enter it here wearable data available prior to subcohort selection on random All Of Us subsample

If you have more than five data items, you may enter them here.

health literacy (validated questionnaire), address (proximity to safe spaces for physical activity), (geolocation), race (survey), ethnicity (survey), income (survey), education (survey), diabetes (EHR), hypertension (EHR), cardiovascular disease (EHR), depression (EHR), anxiety (EHR), arthritis (EHR), sexual orientation (survey), gender identity (survey), self-efficacy (validated questionnaire), executive functioning (validated questionnaire), functional status (survey), age (EHR), lower urinary tract symptoms (survey)

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Idea No. 45