AoU Research Priorities Use Cases

Does the human epigenome reflect exposure to environmental chemicals?

The human epigenome is altered by environmental pollutants, including particulate air pollution, bisphenol A, phthalates, metals, pesticides, dioxin-like compounds, and persistent organic pollutants. All of us will be uniquely positioned to link exposure to environmental chemicals with alterations in the human epigenome. This will require refined measures of environmental exposure that—if measured in All of us—will cause a quantum shift in the understanding of environmental disease.



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Idea No. 813