AoU Research Priorities Use Cases

Evaluate the impact of circadian clock and sleep on health and diseases prevention, progression, and treatment across lifespan

Circadian clock and/or sleep disruptions have been suggested associated with health and disease outcome. A systematic longitudinal follow up over lifespan is needed to understand the underlining mechanisms. All of Us project could provide such opportunity to evaluate the dynamic relationships of circadian clock and sleep with other multi-level factors, such as, lifestyle (diet, exercise and mental health) and behavior, from children to elderly on health outcome.

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Idea No. 847