AoU Research Priorities Use Cases

Evaluate the impact of circadian clock and sleep on health and diseases prevention, progression, and treatment across lifespan

Circadian clock and/or sleep disruptions have been suggested associated with health and disease outcome. A systematic longitudinal follow up over lifespan is needed to understand the underlining mechanisms. All of Us project could provide such opportunity to evaluate the dynamic relationships of circadian clock and sleep with other multi-level factors, such as, lifestyle (diet, exercise and mental health) and behavior, from children to elderly on health outcome.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. sleep time, blood, microbiome, circadian clock genes, immunity

If you did not find your method for obtaining Data Item #1 in the dropdown selection above, please enter it here. clinical and laboratory test and biomarker measurement, fecal sample ,

If Specification #2 was not in the dropdown, please enter it here: daily

If Method #3 was not in the dropdown, please enter it here biomarkers

If Specification #3 was not in the dropdown, please enter it here N/A

Method #4 Blood test

If Specification #4 was not in the dropdown, please enter it here N/A

If Specification #5 was not in the dropdown, please enter it here N/A

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Idea No. 847