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Genetic, epigenetic, and microbiome contributions to hypertension

The goal would be to enhance our understanding of how social and environmental exposures, genomic factors, and gut microbiota interact to influence hypertension susceptibility and phenotype. This would require integrated analyses of genomic and other -omics data, exposures, and phenotype data, and could lead to insights that enable more targeted prevention and treatment. Inherent in this would be discovery of pathways that contribute to disparities in hypertension onset or treatment response.

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Idea No. 561