AoU Research Priorities Use Cases

How do experiences of racial discrimination relate to HPA axis activity and the prevalence of chronic illnesses?

Community Member kudos icon + Community member

Instances of racial discrimination activate the HPA axis, and this chronic activation may be related to the disproportionate prevalence of chronic illnesses in members of racial minority groups. Some studies have found a blunted cortisol concentration in African Americans, compared to Caucasians. However, it's unknown whether all members of racial minority groups have a blunted cortisol concentration, and how it relates to instances of racial discrimination and occurrence of chronic illnesses.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. Daily and lifetime encounters of racial discrimination

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Survey

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Once per year

If Data Item #2 was not in the dropdown, please enter it here. Saliva samples (as a measure of cortisol concentration)

Method #2 Biochemical assay

Specification #2 Quarterly

Data Item #3 History, health

If Method #3 was not in the dropdown, please enter it here Self-reported diagnoses of chronic illnesses; verified through available medical records

Specification #3 Once per year


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Idea No. 281