Chronic stress linked to social disadvantage—economic deprivation, exposure to racism and discrimination, etc.—contributes to health disparities. Social stressors vary across the life course, affecting disease risk, progression and outcomes in disadvantaged groups. All of Us cohort data will shed light on mechanisms by which social disadvantage and chronic stress affect physiology, health behavior and overall health, aiding the development of effective interventions to reduce health disparities.
Idea No. 779