AoU Research Priorities Use Cases

Improving precision management of acute infections and sepsis as a major burden to healthcare systems

Key areas of unmet medical need:

- Improve identification of patients at high risk for sepsis

- Improve characterization of patients with sepsis (endotyping)

- Predict outcomes of acute infections and/or sepsis at the time of presentation

- Develop companion diagnostics (biomarkers?) that identify patients responding to specific sepsis therapies

- Improve early diagnosis of pathogens causing sepsis and their resistance profile

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. Clinical outcomes

Data Item #2 Perceived outcomes - patient

Data Item #3 Epigenetic markers

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Idea No. 490