AoU Research Priorities Use Cases

Investigate impact of pharmacogenomics on real world prescribing practices and medication use

The goal of this study is to understand pharmacogenetic and other predictors of adverse effects of medications and therapeutic failure enabled by aggregation of claims data and pharmacy fill data from multiple sources over many years.

For example, does treatment failure of proton pump inhibitors in genetic hypermetabolizers cause increased surgical procedures and how do drugs interact in patients treated with multiple drugs with overlapping metabolism pathways.

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Idea No. 840