AoU Research Priorities Use Cases
Using human microbiome data to improve pathogenesis and treatment of infectious diseases
Precision microbiome engineering could be applied to vaccine delivery, immunology, drug-resistant infections, and post-surgical infections.
Specific research questions re pathogenesis and treatment:
- What aspects of the indigenous microbiota mediate colonization resistance against C. difficile, as well as other multi-drug resistant organisms such as carbapenamase-producing gram negative bacteria and vancomycin resistant enterococci?
- Determine optimal C. diff treatment to prevent relapse
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Idea No. 492