AoU Research Priorities Use Cases

What GENE(S) is responsible for HYPERSENSITIVITY to inhaled corticosteroids in Asthma patients, and how does it function?

1) Bin asthma patients for hypersensitivity to inhaled corticosteroids (hypersensitivity- "dose dependent slow but steady strangulation"). Improvement may be determined simultaneously, allowing complete characterization of response to treatment, according to drug, dosage, duration of treatment, etc. While this study is limited to inhaled corticosteroids, other drug treatments may be performed similarly.

2) Determine genetic differences: genes, alleles, expression, epigenetic status

3) Correlate

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. Genome

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Idea No. 40