AoU Research Priorities Use Cases

What are the associations between the exposome and health?

Last Edited by Jill Reedy

To understand health effects of the exposome, exposure assessment in population-based research should include measures of all the exposures of an individual in a lifetime, including general external, specific external, and internal. Assessing the exposome requires multiple, repeated longitudinal and hierarchical exposure measurements with sufficient variability; standardized methodology and analysis; and capabilities for linkages among population-based studies, other datasets, and registries.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. General external exposures: including social capital, education, financial status, psychological and mental stress, urban-rural environment, climate, etc.

If you did not find your method for obtaining Data Item #1 in the dropdown selection above, please enter it here. Could be assessed with activity monitor, EHR, mobile monitor, personal air pollution monitor, survey, smartphone ecological momentary assessment, or other measures

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Once per year

If Data Item #2 was not in the dropdown, please enter it here. Specific external exposures: including radiation, infectious agents, chemical contaminants and environmental pollutants, diet, lifestyle factors (tobacco, alcohol), occupation, medical interventions, etc.

If Method #2 was not in the dropdown, please enter it here Could be assessed with activity monitor, EHR, food recall, mobile monitor, personal air pollution monitor, survey, smartphone ecological momentary assessment, or other measures

Specification #2 Once per year

If Data Item #3 was not in the dropdown, please enter it here Internal exposures: including metabolism, endogenous hormones, body morphology, physical activity, gut microflora, inflammation, lipid peroxidation, oxidative stress, aging, etc.

If Method #3 was not in the dropdown, please enter it here Could be assessed with activity monitor, biochemical assay, EHR, mobile monitor, personal air pollution monitor, survey, smartphone ecological momentary assessment, or other measures

Specification #3 Once per year

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Idea No. 676