AoU Research Priorities Use Cases

What are the social, biological and behavioral factors that influence fatigue in adults and children?

Fatigue is commonly reported as prodromal to acute and chronic illness. At this point, we do not understand the etiology of fatigue; it is often confused with sleepiness. Longitudinal assessments of self-reported symptoms (fatigue, sleep, pain, depression), comorbid conditions, physical activity, and biomarkers will be collected monthly over 1 year to allow us to assess potential temporal effects of fatigue on daytime and nighttime (sleep) activity patterns in adults and children.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. Yes

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. Fatigue

If you did not find your Data Item #1 in the dropdown selection above, please enter it here. inflammatory biomarkers

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. ELISA

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Quarterly

Data Item #2 History, health

If Data Item #2 was not in the dropdown, please enter it here. self report

Specification #2 Once per year

Data Item #3 Fatigue

If Data Item #3 was not in the dropdown, please enter it here self-report (pateint reported outcome) PROMIS measures

Specification #3 Quarterly

If Data Item #4 was not in the dropdown, please enter it here sleep quality self report (PROMIS measures)

If Method #4 was not in the dropdown, please enter it here PROMIS measure

Specification #4 Quarterly

If Data Item #5 was not in the dropdown, please enter it here daytime and nighttime activity (sleep)

If Method #5 was not in the dropdown, please enter it here actigraphy

If Specification #5 was not in the dropdown, please enter it here hip and wrist

If you have more than five data items, you may enter them here.

social history

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Idea No. 548