AoU Research Priorities Use Cases

What environmental and genetic factors influence the development of osteoarthritis?

Osteoarthritis (OA) is the most common cause of disability in the United States, and there are no available biomarkers or disease-modifying therapies for OA. Currently, we are unable to identify rapidly progressive OA patients at diagnosis. All of Us offers a unique opportunity to obtain clinical data and biospecimens, along with diet and exercise information, which associate with rapidly progressive OA to help foster development of novel therapies and improved outcomes.

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Idea No. 815