AoU Research Priorities Use Cases

What factors are involved in loss of fecundity in males and females?

This study will focus on the entire cohort across the reproductive lifespan (ages 12-55) collecting data on fertility (time to conception) and pregnancy loss. Additional data will include factors believed to be indicators of fertility as determined by questionnaire, blood tests, factors believed to negatively impact fertility, and genetic/epigenetic data that together may provide new targets for understanding oocyte depletion, worsening semen analyses, and pregnancy loss.

The remaining questions allow you to outline in more detail the information needed to address your research question. The series of questions allow up to five entries. If you have more than five entries, please try to prioritize them and enter the remainder in the final field. When done, click Submit at the bottom. No

Select your required Data Item #1, which is most important to your study. This would be an item that needs to be generated and collected from different sources using various procedures, tools, techniques, assays, etc. If not in the current selection, please enter it in the textbox below. History, obstetric

By what method will Data Item #1 be obtained? This may Include procedures, tools, techniques, assays, and analytical approaches for the collection, measurement, or analysis of data. If you do not find the required method, you may enter it in the textbox below. Electronic Health Records (EHR)

Are there specifications that apply to the method by which Data Item #1 will be obtained, e.g., is the measurement taken once a year, every month, or some other variation? If you do not find your specification in the dropdown, you may enter it in the textbox below. Once per year

If Data Item #2 was not in the dropdown, please enter it here. Reproductive health and indicators of fertility

Method #2 Survey

Specification #2 Once per year

If Data Item #3 was not in the dropdown, please enter it here FSH and AMH

Method #3 Blood test

Specification #3 Once per year

Data Item #4 Genome

Method #4 Whole Genome Sequencing (WGS)

Specification #4 Once

Data Item #5 Environmental exposure

Method #5 Survey

Specification #5 Once per year

If you have more than five data items, you may enter them here.

-Participant provided information spanning the following fields: age, sex/gender, sociodemographic, social history, and ethnicity
-Mobile monitors to provide physical activity data
-Electronic Health Record provided information spanning the following fields: medication history, tobacco use, alcohol and drug use, mental health history, disease diagnosis history
-Physical examination providing: height, weight, waist circumference
-Semen samples

Voting

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Idea No. 79