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What if any are the differences in health outcomes for genetic versus self-reported demographics?

What if any are the differences in terms of cancer incidence and treatment outcomes for genetic demographics (biological sex, ethnicity) versus comparable self-reported demographics (gender, race, nationality)? The goal of this research would be to explore the relative contribution on disease, health, and outcome of genetically determined demographic characteristics versus personal, social or culturally determined demographic characteristics.

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Idea No. 21