Showing 2 ideas for tag "agonist"
(@arianasmith) kudos icon +

AoU Research Priorities Use Cases

In Overactive Bladder does pharmacogenomics influence individual response to antimuscarinic and beta-agonist bladder medication?

Overactive bladder is highly prevalent with significant impact on quality of life. Medications are utilized despite variable efficacy, high side effect burden, and poor persistence on therapy. This study will identify an overactive bladder cohort who have been prescribed antimuscarinic or beta-agonist medication to relieve symptoms. We hypothesize relief of symptoms will be based on the individuals pharmacogenomics. Personalized... more »

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(@kevin0) kudos icon +

AoU Research Priorities Use Cases

Can widespread use of Endomorphin 1 & 2 end the opioid overdose crisis? They don't cause respiratory depression or addiction.

Endomorphine is a highly selective mu but not delta or kappa receptors which cause all the unwanted side effects of opioids.
Goals - Prove Endomorphin's superiority to other opioids.
Methods - Monitor pain levels, addiction through tox screens and mortality rates from overdose.
Expected outcome - Endomorphin will have very low if any overdoses, tolerance build up should be minimal, alcohol addiction should be reduced,... more »

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