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How does environmental airborne exposures affect nasal symptoms and disease (rhinitis, chronic sinusitis)?

Collect symptom diaries from individual across a range of exposures and correlate exposures with disease; determine if genetics, health characteristics, and demographic are associated with airway disease. Measure nasal inflammation and microbes in a subset of patients to determine mechanisms. Determine if genotype affects symptoms. Determine if there is an epigenetic signature of exposure in nasal epithelium and correlate... more »

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