An estimated 1.6 million American adults live with Congenital Heart Disease (CHD), with this group growing at the rate of 40,000 to 50,000 people yearly. This sensitized population have a much higher risk to get cardiovascular diseases.
Collecting DNA samples and heart health data to detect how those factors contribute to their heart health. Identification of the risk factors will not only improve life quality and life... more »

Heart attack and stroke lead to over half a million deaths in the United States annually. It is now possible to predict these cardiovascular events well in advance using a number of biomarkers related to vascular structure and function. Collecting such noninvasive biomarkers as part of the All of Us cohort will allow us to fine-tune this timeline prediction.

Genetics can be the earlier risk predictor of common, heritable traits such as atherosclerotic cardiovascular disease (ASCVD). Longitudinal environmental exposures and behavioral practices subsequently modify risk. Uniform dense ascertainment of environmental exposures and behavior is feasible through wearable sensors. We and others are beginning to look at the comprehensive set of exposures that influence ASCVD risk.... more »

Numerous research has shown that cardiovascular health declines from childhood through adulthood. The preservation or promotion of ideal cardiovascular health is influenced by biological, environmental and behavioral factors including diet, physical activity, smoking status, body mass index and biomedical indices such as blood glucose, blood pressure and blood lipids.