Showing 2 ideas for tag "diabetic-kidney-disease"
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Will the clinical use of predictive glycation and oxidation biomarkers improve diabetes care and prevent long-term complications

Since diabetic complications occur in those that show more glycative and oxidative stress, we have validated their predictive power in ground-breaking outcome trials to create diagnostic blood tests for clinical use.
To study the clinical efficacy and utility of these tests we will identify those at high risk (HR) before DKD and CVD are apparent. Primary endpoints are achievement of rigorous glycemic and proposed treatment... more »

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AoU Research Priorities Use Cases

What factors are associated with albuminuric and non-albuminuric diabetic kidney disease, and with the eGFR reduction over time?

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), the most serious and expensive stage of chronic kidney disease (CKD). Pre-ESRD stages of CKD are also associated with significant health care burden. DKD can progress to ESRD with or without albuminuria. Better understanding of risk factors attributable to the development of albuminuric and non-albuminuric DKD, and to their progression... more »

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