Research on populations underserved in biomedical research (UBR) is often based on single UBR characteristics or combined age-race-ethnicity-sex groupings. However there are population subgroups with particularly concerning constellations of UBR characteristics and very poor health status (e.g., persons without health insurance who live in rural Appalachia). All of Us can provide a more complete picture of the extent,... more »

Careful and extensive characterization of lifetime environmental exposures and chronic disease phenotypes in the All of Us population; determination of genetic risk factors for various exposure and disease combinations; follow-up for chronic disease outcomes.