Showing 30 ideas for tag "health"
(@jvolcken) kudos icon +

AoU Research Priorities Use Cases

What about our environment drives us to become healthy?

We are trained to conduct research to elucidate the causes of morbidity and mortality. A study designed to understand the cause of a given disease, however, is not the same as one designed to understand the root causes of health and quality of life. I suspect there is more to being healthy than riding a bike and eating green vegetables...let's work to find out and then apply that knowledge to design homes, schools, communities... more »

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11 votes
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(@sjayo8585) kudos icon +

AoU Research Priorities Use Cases

Establish a link between sensory analytics (SA) and health and mortality outcomes. SA will be at the heart of telemedicine.

The future of medicine will include not just traditional in-person visits between doctors and patients, but the rise of telemedicine will enable health care professionals to "visit" and evaluate the health status of people thousands of miles away -- in real time. The remote diagnosis of health conditions, establishment of treatment protocols, and administration of needed interventions, will address underserved populations... more »

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5 votes
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(@cavin.ward) kudos icon +

AoU Research Priorities Use Cases

What are the molecular factors of heightened sensitivity to air pollution?

Defining heightened sensitivity as an increased hazard ratio for an association between air pollution and a health outcome, identify subsets of the population based on molecular factors, e.g. genetic variants, hypermethylated regions, which are at increases risk of adverse cardiovascular or pulmonary events during high air pollution days.

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5 votes
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(@jberghout) kudos icon +

AoU Research Priorities Use Cases

What are the best genetic indicators of wellness?

Wellness is not just absence of disease. But it is challenging to define aside from by disease exclusions. EHR data can't (easily) discriminate absent info. vs. evidence for absence of health concern. However, we (participants) know it when we feel it. Longitudinal data on self-reported "excellent" health, #minor illnesses/exacerb. (i.e. colds, non-critical injury, minor symptoms of chronic cond.), vital signs & etc can... more »

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7 votes
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(@jenna.norton) kudos icon +

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Can inclusion of erectile dysfunction (ED) improve prediction of incident cardiovascular disease (CVD)?

Recent epidemiological evidence shows ED is associated with CVD, suggesting ED may be a prodrome of CVD. We proposed to assess associations between ED preceding CVD to confirm this association in the large and diverse All of Us cohort. Additionally, ED will be added to the existing Framingham risk prediction equation to determine if inclusion of ED improves the model.

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7 votes
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(@jaime.gahche) kudos icon +

AoU Research Priorities Use Cases

Why assess diet and dietary supplements in the population?

Over half of US adults and one-third of children take at least one dietary supplement. Combined with intakes of foods, total nutrient intake can be estimated and linked to health outcomes in etiologic research. Such population data can inform guidance, such as the Dietary Guidelines for Americans and Dietary Reference Intakes. Supplements may be warranted for sub-groups where nutritional requirements may not be met through... more »

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5 votes
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(@gdemmler) kudos icon +

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What are the health economics impact of congenital cytomegalovirus ( CMV) infection, the most common congenital infection?

Congenital cytomegalovirus (CMV) infection is the most common congenital infection, and a common cause of neurodevelopmental disabilities, growth failure, hearing loss and vision loss. Prevention of congenital CMV by vaccination was deemed a national priority for the 21st century by the Institute of Medicine in 2000. Information on the health economics of this common congenital infection is necessary to drive prevention... more »

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3 votes
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(@laura.dwyer) kudos icon +

AoU Research Priorities Use Cases

How does the social environment contribute to health behaviors and outcomes within intimate relationships?

There is insufficient knowledge about relationship-level factors in couples to adequately inform precision behavior change interventions. Existing interventions largely do not account for how the social environment contributes to lifestyle behaviors and that these behaviors are often done with others, or in response to our relationships (i.e., couples). The All of Us cohort presents a unique opportunity to survey cohort... more »

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4 votes
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(@lisa.signorello) kudos icon +

AoU Research Priorities Use Cases

To develop or optimize a non-invasive BIOMARKER that can be used to measure the experience of stress in children and adults.

The impact of psychosocial stress on child and adult health risk is increasingly appreciated. The measurement of this exposure is currently poor, and All of Us has the opportunity to develop or refine biomarkers that could help push this field of research forward in a valid way for the future. Such biomarkers could be a part of individual studies of stress and disease, and could also be used as a gold standard to develop... more »

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3 votes
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(@lisa.signorello) kudos icon +

AoU Research Priorities Use Cases

To develop/refine novel technologies (related to GPS or GIS) that could help us better define community contextual exposures.

The built environment is only one contextual exposure of interest to investigators who study these factors in relation to disease (and even these function variably across rural and urban areas). New technology could assist in better clarifying a fuller scope of residential exposures, including what elements/exposures the All of Us participants actually come into contact with.

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1 vote
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(@sluckhaupt) kudos icon +

AoU Research Priorities Use Cases

How do contract and contingent (temporary) work arrangements affect worker health?

More than 90% of all job growth in the US from 2005-2015 occurred in “alternative work arrangements” (e.g., part-time or contract work). This has provided flexible employment opportunities, but negative effects on health. AoU could look at how contract and contingent workers cope with job insecurity, lack of health and retirement benefits, and absence of job safety policies and training, and how these affect mental health,... more »

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1 vote
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(@gerhild.ullmann) kudos icon +

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What are the health benefits of mind-body exercises such as Feldenkrais, tai chi, yoga etc.?

Health benefits of mind-body exercises are 'under-researched' compared to health benefits of aerobic exercises. Many people do not meet the current physical activity recommendations for maintaining health, in particular older adults and individuals with chronic health issues. Thus, it is of high importance to facilitate the potential health effects of mind-body exercises. Funding for well-designed randomized controlled... more »

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1 vote
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(@katiew) kudos icon +

AoU Research Priorities Use Cases

Risk and protective factors for alcohol and other drug use disorders, as well as associated health outcomes.

More than 1 in 5 Americans meet lifetime criteria for alcohol use disorder and 1 in 10 Americans meet lifetime criteria for a drug use disorder. Most individuals never seek treatment and most reduce their alcohol or drug use in the absence of treatment. Research on the biological, psychological, and social risk factors for developing and recovering from alcohol/drug use disorders is critical. Annual assessments of DNAm,... more »

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1 vote
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(@mbl2018) kudos icon +

AoU Research Priorities Use Cases

How do our mindsets about diet, exercise, and stress influence health behaviors and health outcomes?

Research has shown that benefits of health behaviors such as diet, exercise, and stress depend not just on the behaviors themselves but on the mindsets people have about those behaviors (Crum, Achor & Salovey, 2013; Zahrt & Crum 2017; Turnwald, Boles & Crum 2017); however, large-scale databases have not yet included measures of mindset. The goal of this study is to use validated measures of exercise, stress and diet mindsets... more »

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