Showing 3 ideas for tag "pregnancy-associated"
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Preconception predictors of preterm birth

Given the limited effects of current interventions to prevent preterm birth, it seems likely that the stage for adverse pregnancy outcomes is set even before the pregnancy begins. The All of Us cohort, if sufficient reproductive-aged women are enrolled, would be in a position to examine social, behavioral, medical, and biological/molecular predictors of preterm birth and its subtypes.

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AoU Research Priorities Use Cases

Bridging the gap between obstetric history (preeclampsia) and future women's health and cardiovascular outcomes

2 possible designs:
1) Enroll women diagnosed with preeclampsia (PEC) during current pregnancy and collect data (phenotype & biomarkers), follow up prospectively until cardiovascular events (acute coronary events, strokes, including cardiac surgery)
2) Ambidirectional design: enroll women with a PEC history now having cardiac surgery/cardiopulmonary bypass (CPB); collect biomarkers & clinical outcomes (phenotype after... more »

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AoU Research Priorities Use Cases

What are the health economics impact of congenital cytomegalovirus ( CMV) infection, the most common congenital infection?

Congenital cytomegalovirus (CMV) infection is the most common congenital infection, and a common cause of neurodevelopmental disabilities, growth failure, hearing loss and vision loss. Prevention of congenital CMV by vaccination was deemed a national priority for the 21st century by the Institute of Medicine in 2000. Information on the health economics of this common congenital infection is necessary to drive prevention... more »

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