Key areas of unmet medical need:
- Improve identification of patients at high risk for sepsis
- Improve characterization of patients with sepsis (endotyping)
- Predict outcomes of acute infections and/or sepsis at the time of presentation
- Develop companion diagnostics (biomarkers?) that identify patients responding to specific sepsis therapies
- Improve early diagnosis of pathogens causing sepsis and their resistance... more »

This study will focus on the entire cohort of children (infants-18 y/o) and will identify those risk factors which predispose children to sepsis. The information will be used to create more precise strategies to identify individuals at highest risk of sepsis and to implement preventive or early treatment therapies that would improve outcomes. The study will also assess the use of adjunctive immunomodulatory therapies... more »