Showing 5 ideas for tag "surgery"
(@jenna.norton) kudos icon +

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What characteristics define women with Urinary Incontinence who respond to midurethral sling surgery, versus those who don’t?

Midurethral sling surgery (MuSS) outcomes are inconsistent. We lack knowledge of outcome moderators. This study will identify a prospective subcohort of women aged 18+ with incident successful and unsuccessful MuSS. Hypothesized moderators of MuSS outcome spanning the social ecological model (e.g., urinary microbiome, comorbidities, BMI, physical activity, race, occupation, income) will be compared across those with successful... more »

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20 votes
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Does midurethral sling surgery (MuSS) for stress urinary incontinence (SUI) improve metabolic risk profile?

SUI may contribute to reduced physical activity and poorer adherence to diuretics, thereby increasing metabolic risk profile. This study will identify a prospective subcohort of women aged 18+ with incident MuSS to compare metabolic risk profile before and after successful surgery. We hypothesize successful MuSS will decrease need to urinate during day, increase level of physical activity, and reduce metabolic risk. Patient... more »

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17 votes
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Persistent opioid use after surgery in previously opioid naive patients

The fundamental question in addiction research is why some people become addicted while others who are exposed abused substances do not. There is an opportunity to answer this question for opioid addiction and respiratory depression in surgical patients. About 5 to 10 percent of surgical patients who are pain free and opioid naïve, given opioids during and after surgery, persist in opioid use 12 months after surgery... more »

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15 votes
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Bridging the gap between obstetric history (preeclampsia) and future women's health and cardiovascular outcomes

2 possible designs:
1) Enroll women diagnosed with preeclampsia (PEC) during current pregnancy and collect data (phenotype & biomarkers), follow up prospectively until cardiovascular events (acute coronary events, strokes, including cardiac surgery)
2) Ambidirectional design: enroll women with a PEC history now having cardiac surgery/cardiopulmonary bypass (CPB); collect biomarkers & clinical outcomes (phenotype after... more »

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11 votes
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(@jenna.norton) kudos icon +

AoU Research Priorities Use Cases

What characteristics define women with Urinary Incontinence who respond to midurethral sling surgery, versus those who don’t?

Midurethral sling surgery (MuSS) outcomes are inconsistent. We lack knowledge of outcome moderators. This study will identify a prospective subcohort of women aged 18+ with incident successful and unsuccessful MuSS. Hypothesized moderators of MuSS outcome spanning the social ecological model (e.g., urinary microbiome, comorbidities, BMI, physical activity, race, occupation, income) will be compared across those with successful... more »

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10 votes
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