Showing 3 ideas for tag "type-1-diabetes"
(@ssr4n0)

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Understanding the pathogenesis of type 1 diabetes

Use a case-cohort study, identifying cases through the EHS system and confirming through a variety of clinical laboratory tests. We know little about the genetic basis of T1D in African-ancestry (non-white) populations or T1D with onset in adulthood, These data would also provide insights on the rates and types of complications that may differ between adult-onset T1D and childhood-onset T1D.

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(@hstuckey)

AoU Research Priorities Use Cases

How does the effect of childhood trauma affect the self-managment behaviors (and A1c) of Type 1 diabetes in adults?

I would use the Childhood Adverse Events scale to identify those who have experienced childhood trauma, and compare that with A1c and the SDSCA behaviors. Then, I would conduct interviews to those who are open to further inquiry, regarding HOW they believe that childhood trauma effects their glucose control on a daily basis.

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(@chymlarisma)

AoU Research Priorities Use Cases

how can intravenous insulin therapy help diabetics in controlling their disease in an out patient scenario?

This is 26-wk study of 60 patients in 2:1 ratio, cohort 1 on standard of care (SOC) & IV Insulin Infusion vs SOC alone for diabetes. Patients labs (HA1c, C-peptide, Insulin, CrClearance), BP, HR, and evidence of Neuropathy, retinopathy, nephropathy, Fatigue and hypertension will be measured at the beginning of the study, then every 12 weeks thereafter. After the first 12 weeks, the cohort 2 will cross-over to cohort... more »

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