This study will focus on women who are pregnant at enrollment or become pregnant during the study and the offspring of observed pregnancies. The information will help to define genetic and epigenetic predictors of long-term effects of common pregnancy complications.
There is a lot of controversy on whether a disease can be treated based primarily on a change of diet. With this study I would test the theory with participants from various groups to determine if the condition could be improved through diet and also determine is medication is needed for improvement
Methods: Community-based participatory research. Testing concordance of race/ethnicity of facilitators and participants.
Outcomes: Increased minority participation... more »
Changes involved in the progression of T2D and development of complications is apparent at the pre-DM state or during the transition to T2D or with complications. Conducting ‘Omics’ including DNA methylation, metabolomics and microbiome studies in blood, saliva and Fecal samples allows to validate interactions of metabolites to microbiota to epigenetic regulations.