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What genetic factors and environmental factors are associated with dental caries?

Dental caries affects 90% of US adults and is more severe in underserved populations. Caries is caused by a complex biofilm and severity is influenced by dietary intake of sugars. Recent studies have identified caries-susceptibility alleles, some of which may be modified by fluoride use. However, more studies are needed in diverse populations. Understanding genetic factors influencing dental caries may improve caries... more »


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