Recent findings from 15,744 black and white adults in the ARIC Cohort Study found that several cardiovascular (CV) risk factors in middle age (smoking, diabetes, prehypertension & hypertension) are linked to higher risk of dementia later in life, and that blacks have higher rates of dementia v. whites. AoU offers ability to evaluate differential associations of specific CV risk factors, & their interactions with other... more »

Social and environmental factors (e.g., poverty, strain, environmental toxins) may affect the risk of premature aging as measured through bone density, and they may be linked to measures of inflammation. Data are needed on markers of inflammation, stress processes, bone density, subjective and objective environmental data, measures of social support and strain, detailed measures of socioeconomic status, measures of state... more »