Showing 2 ideas for tag "prematurity"

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Preconception predictors of preterm birth

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Given the limited effects of current interventions to prevent preterm birth, it seems likely that the stage for adverse pregnancy outcomes is set even before the pregnancy begins. The All of Us cohort, if sufficient reproductive-aged women are enrolled, would be in a position to examine social, behavioral, medical, and biological/molecular predictors of preterm birth and its subtypes.

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AoU Research Priorities Use Cases

What factors contribute to the disparate respiratory (and cardiovascular) outcomes of infants born prematurely?

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Infants born at <28 weeks of gestation who survive can experience long-term impacts from subtle abnormalities in respiratory function to profound disability including asthma, early COPD, or long-term dependence on mechanical ventilation. It is unclear how maternal environmental exposures, geographic differences, social factors, or genetic predisposition in the pre-conceptional period or during pregnancy might contribute... more »

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