AoU Research Priorities Use Cases
AoU Research Priorities Use Cases
What are the genetic and environmental risk factors that contribute to the broader autism phenotype in adolescents and adults?
Voting
AoU Research Priorities Use Cases
Criteria for Environmental Associated Autoimmune Diseases
Goal: Survey patients with autoimmune diseases for information on occupational and other life style exposures to factors associated with autoimmunity (smoking, silica dust, solvents, etc). Build data bases containing clinical parameters, blood tests, and exposure data to help identify putative diagnostic criteria. Compare with patients having idiopathic autoimmunity (i.e. lacking known risk exposures)
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AoU Research Priorities Use Cases
Can pollen allergies be isolated by genetics, confirmed by allergy testing, and exposure be tracked to limit asthma attacks?
Voting
AoU Research Priorities Use Cases
What factors are involved in loss of fecundity in males and females?
Voting
AoU Research Priorities Use Cases
Which genetic and environmental factors contribute to sexual orientation, and related health conditions?
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AoU Research Priorities Use Cases
How do exposures to multiple environmental stressors impact chronic disease risk
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AoU Research Priorities Use Cases
Preconception predictors of preterm birth
Given the limited effects of current interventions to prevent preterm birth, it seems likely that the stage for adverse pregnancy outcomes is set even before the pregnancy begins. The All of Us cohort, if sufficient reproductive-aged women are enrolled, would be in a position to examine social, behavioral, medical, and biological/molecular predictors of preterm birth and its subtypes.
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AoU Research Priorities Use Cases
How do environmental exposures and social factors interact to influence the risk of chronic disease?
N/A
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AoU Research Priorities Use Cases
What are the impact of common environmental exposures on cardiovascular (CV) and other health outcomes?
Voting
AoU Research Priorities Use Cases
What are the genetic and/or environmental causes of Meniere’s Disease. Is there an inflammatory component?
N/A, I’m not a scientist.
Voting
AoU Research Priorities Use Cases
What is the the population shift in prevalence of chronic disease with past environmental exposures (esp in older persons)
Careful and extensive characterization of lifetime environmental exposures and chronic disease phenotypes in the All of Us population; determination of genetic risk factors for various exposure and disease combinations; follow-up for chronic disease outcomes.
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AoU Research Priorities Use Cases
How environmental chemicals mediate/influence comorbid chronic diseases?
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AoU Research Priorities Use Cases
Environmental Exposures in the Ohio-Mississippi River Basin: The Missing Link to Obesity
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AoU Research Priorities Use Cases