Showing 3 ideas for tag "pharmacogenetics"
(@pharmgkbfeedback) kudos icon +

AoU Research Priorities Use Cases

Do tailored educational materials for patient-participants undergoing pharmacogenetic testing promote patient engagement?

To assess and compare the level of understanding, engagement and satisfaction in patients who received pharmacogenetic results and are randomized to 1) a web-based portal with personalized educational content tailored to subject's results or 2)standard of care. Subjects will be surveyed to determine 1) understanding 2) engagement and 3) satisfaction.

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15 votes
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(@grizac) kudos icon +

AoU Research Priorities Use Cases

What medications work best for people with epilepsy?

Aim 1. Pharmacoepidemiology. Among people with epilepsy subtypes, what are the most commonly used medications?

Aim 2. Comparative Effectiveness. For each epilepsy subtype, which medication works best?

Aim 3. Pharmacogenetics. Within epilepsy subtypes, what genetic markers predict response to treatment?

(Epilepsy subtypes might include new onset focal epilepsy, new onset generalized epilepsy, Dravet syndrome, Doose... more »

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12 votes
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(@ekarlson) kudos icon +

AoU Research Priorities Use Cases

Can we use an mHealth app to track rheumatoid arthritis symptoms and conduct pharmacogenetics analyses for biologic drugs?

Goals: To determine genetics of response to biologic drugs in RA
Methods: Define RA with EHR algorithm, use mHealth app to record RA symptoms (RADAI), current/new meds + adherence
Outcome: daily RA disease activity after drug start
Data: EHR meds, ESR, CRP; PPI confounders, demographics, smoking, exercise.
Limitations of prior studies: small samples, no adherence or confounder info, sparse outcome data
Expected outcomes:... more »

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2 votes
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