AoU Research Priorities Use Cases
AoU Research Priorities Use Cases
Reduce the burden of sudden cardiac death by identifying individuals who benefit the most from the implantable defibrillator.
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AoU Research Priorities Use Cases
What neighborhood conditions promote health?
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AoU Research Priorities Use Cases
How do local, regional, state, and national retail food environments and policies affect diet and health?
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AoU Research Priorities Use Cases
How reliably do epigenetic aging clocks predict disease onset and mortality? Can they be slowed or reversed?
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AoU Research Priorities Use Cases
What is the population genetics of genes that code for drug-metabolizing enzymes? Do any correlate with drug reactions?
2) Describe the population genetics of these specific genes. How many people are normal (extensive metabolizers, EMs)? How many have other profiles? How many genes is the "average person" abnormal for?
3) By collecting data for "allergies" (some of which are intolerances, not true allergies) and medication reactions requiring... more »
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AoU Research Priorities Use Cases
Do blood biomarkers predict mood transitions for peripartum mood disorder (PPMD)?
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AoU Research Priorities Use Cases
What are the determinants of risk for different breast cancer subtypes?
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AoU Research Priorities Use Cases
How do environmental exposures, behavior, & genetics, in combination, influence risk of atherosclerotic cardiovascular disease.
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AoU Research Priorities Use Cases
Exposures to environmental chemicals during pregnancy and effects on epigenetic biomarkers of metabolic syndrome and obesity
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AoU Research Priorities Use Cases
Is mammographic breast density causally related to breast cancer and/or an intermediate risk factor for breast cancer?
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AoU Research Priorities Use Cases
What characteristics are associated with urinary stone recurrence in persons with prior episode of urinary stone disease?
Urinary stone disease is burdensome and costly, and frequently recurs. Via the EHR and qualitative/quantitative methods, we will identify person and intervention characteristics associated with urinary stone recurrence. Factors associated with recurrence may provide potential treatment targets for preventing stone recurrence.
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AoU Research Priorities Use Cases
Treatments to reduce risk of stroke following a transient ischemic attack (TIA)
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AoU Research Priorities Use Cases
Within a healthy cohort, can genomic and social determinants be used to tailor preventive and primary care recommendations?
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AoU Research Priorities Use Cases