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AoU Research Priorities Use Cases

What are the phenotypic and genetic factors associated with behavioral addictions?

Behavioral addictions (e.g., hair pulling, skin picking, gambling, internet addiction, etc.) are common chronic problems involving shared neural mechanisms (e.g., dopamine dysfunction) and repeated urges to engage in harmful acts. To enhance knowledge of underlying mechanisms and inform treatment development we will identify phenotypic (i.e., comorbidity, affect, impulsivity, reward, sensory measures) subtypes using latent... more »

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AoU Research Priorities Use Cases

Could the Precision Medicine Initiative Help Identify People with Cardiovascular Disease

We will use non-invasive wearable monitoring sensors, similar to a band-aid on the wrist, that measure arterial wave forms at the radial artery in the wrist, providing information on the elasticity and function of cardiovascular system. The information will be uploaded to smartphones and correlated with age and known cardiovascular risk factors, allowing to develop computational models to rapidly identify people at risk... more »

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