AoU Research Priorities Use Cases
AoU Research Priorities Use Cases
Develop a Social-Determinants-of-Health risk calculator for chronic disease development (cardiovascular, Type 2 Diabetes, etc)
Voting
AoU Research Priorities Use Cases
Can metabolite profiles improve disease prediction and management?
The window of opportunity for disease prevention in at-risk individuals may be before symptoms occur and blood/urine chemistries indicate a problem. Considering that one’s metabolome reflects both genetic and environmental influences, could metabolite profiles be explored in the All of Us biospecimens and assessed as diagnostic tools?
Voting
AoU Research Priorities Use Cases
Does physical activity done at an intensity lower than currently recommended reduce the risk of developing cancer?
We propose to investigate risk of developing cancer in a cohort of 100,000 AoU participants using NCIs Activities Completed over Time in 24-hours (ACT24) recall system (doi.org/10.1249/MSS.0000000000001428), and research grade accelerometers. Cases of incident cancer will be captured via linkage to state cancer registries.