There are a lot of unknowns when it comes to the quality of care via Telemedicine. I would like to focus on patient outcomes as it relates to providing safe, reliable and consistent results. The study could be implemented so that both subjective data and objective data are measured. Accessing EHR records and implementing surveys of those patients who suffer from chronic conditions are two methods for collecting pertinent ...more »

We would assess the benefits of health apps on individuals' health on multiple survey and clinical diagnostic items and compare results between three groups. Group 1: no access to a smart phone; group 2: access to a smart phone, but no use of health apps; group 3: access to a smart phone and use health apps. The goal of this data would be to better develop and design mHealth interventions to improve health outcomes.

Study biphobia, bi-erasure and lack of acceptance from the gay and lesbian community. Study how lack of community is detrimental.

If specific nutrients are linked to specific disease/ health outcomes, then to what extent (if any) is ancestry, sex, age, weight, physical activity, dietary patterns (and supplement use), and/or zip code (environmental stressors) expected to impact an individual’s physiological needs/ requirements for a specific nutrient(s)? Consider the use of regression models to determine which factors (in synergy and/ or in isolation) ...more »

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Little is known about the nervous system's role in cancer. Interplay of neural and immune system pathways may play an important role in cancer.

Please consider facilitating and accelerating robust validation of assays, technologies and methods using resources (such as biospecimens) collected in the AoU.

The McLean Hospital/Harvard Medical School Spirituality & Mental Health Program (see http://www.mcleanhospital.org/programs/spirituality-and-mental-health-program) is developing a 6-item self-report survey measure to assess for positive and negative aspects of spiritual/religious life. Inclusion of the items in the All of Us protocol could facilitate powerful exploratory analyses to assess how this domain is related to ...more »

One possible design for examining how perceived safety is associated with different facets of our lives is to include the P-SAFE scale (measuring different facets of safety such as perceived safety, fear of crime, neighborhood walkability, and examine its association/correlation with other measures included in the study (positive/negative life outcome, well-being and other related measures). This will allow for future ...more »

The consequences of concussion on cognition, especially repeated concussion, is a major concern in the US. The ABCD research program is assessing the effects of concussion on behavioral health in children but there are no other population studies of concussion effects. Obtaining information about index events and incorporating it into follow-up assessments of cognition and diagnosis of dementia would be extremely valuable ...more »

The shared goal of NIH and the participants is to reduce the burden of illness across conditions and segments of the population. How to capture burden of illness due to this variety of health conditions on an individual basis? A validated, standardized measure of disability would be extremely valuable to ascertain the impact of the various conditions on function in All of Us. Plan might be to assess the various, validated ...more »

To better understand variants relevant to African-Americans and their disease risk it would be helpful to have data on reference African populations from the African ethnic groups with the greatest historical genetic contribution through the transatlantic slave trade. Naturalized U.S. citizens born in Africa would be more easily accessible to regional sequencing leaders (e.g. Houston has the largest Nigerian U.S. population ...more »

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