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IGA is secreted in breast milk. Could this be a possible treatment method for those in which they have issues in organs where a lack of IGA may trigger disease bc IGA does play such a crucial role in the immune function of mucous membranes, and therefore a lack of puts those at risk. Goals-treat diseases by bringing body more into balance versus taking blocking inflammatory from signaling proteins.

Is Isoniazid treatment for +PPD associated with food intolerance and/or granuloma annulare?

Many illnesses are rooted in food allergies causing years of pain & tremendous costs.

This study will focus on the entire cohort (menarche through lifespan) to collect data on general health and wellbeing as well as detailed pregnancy & delivery histories. Activity level will be monitored, specifying any straining associated with either physical activity or occupation. Genetic/epigenetic factors, such as family history of POP or connective tissue disorders will be obtained, as will data on other currently... more »

Follow a subsample of all infants and children (< 3 years of age) throughout childhood to obtain the following serial assessments: blood tests, medication history, neonatal, infant and childhood health outcomes; physical measurements and laboratory microbiologic evaluations of oral, skin and vaginal specimens. Assessments and measures would be used along with health outcomes to determine associations and develop predictive... more »

This study will focus on the entire cohort of children (infants-18 y/o) and will identify those risk factors which predispose children to sepsis. The information will be used to create more precise strategies to identify individuals at highest risk of sepsis and to implement preventive or early treatment therapies that would improve outcomes. The study will also assess the use of adjunctive immunomodulatory therapies... more »

This study will focus on the entire cohort (infant-19 y/o) to provide health and behavior outcomes associated with sleep characteristics, including environmental and demographic factors. This information will help better define the development of sleep, help develop more precise strategies to target children with sleep characteristics predictive of poor health outcomes, and develop more precise strategies for children... more »

This study will focus on women who are pregnant at enrollment or become pregnant during the study and the offspring of observed pregnancies. The information will help to define genetic and epigenetic predictors of long-term effects of common pregnancy complications.

From a diverse sample of children in both clinical and non-clinical settings, investigate genetic contributions to a wide range of neurodevelopmental problems (NPs). Individual-variant and polygenic approaches can advance our understanding of the genetic overlap between, and specificity in, different types of NPs. In a large and diverse sample that includes different racial/ethnic and socioeconomic groups, these techniques... more »

Each year sudden cardiac arrest (SCA) strikes over 300,000 Americans, and ~90% die unless given CPR and/or an electric shock from an AED. While SCA is linked to some heart conditions, there is much to learn about the role of various genes, dietary factors, environmental toxins, some pharmaceuticals, and emotional stressors. It is recommended that a cohort of SCA survivors (with ICDs to prevent death) be included in... more »

Given the limited effects of current interventions to prevent preterm birth, it seems likely that the stage for adverse pregnancy outcomes is set even before the pregnancy begins. The All of Us cohort, if sufficient reproductive-aged women are enrolled, would be in a position to examine social, behavioral, medical, and biological/molecular predictors of preterm birth and its subtypes.

How can a study be accurate if the routine of the patient is changed?

Epidemiological study of exercise habits and outcomes in samples with physical disability

Precision ought to show what non-ionizing battery causes to average active people.