(@michelle.d.novak)

AoU Research Priorities Use Cases

What are the long term effects of biopharmaceuticals (biologics) on children exposed in utero?

Tens of millions of Americans are effected by autoimmune diseases, a majority of which are women. Biopharmaceuticals are prescribed even during pregnancy. It is assumed maternal health is monitored closely as it fetal health, however, what are the long term effects on the child's health and how do biopharmaceuticals effect those children's long term disease risk profiles.

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1 vote
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(@diane.newman)

AoU Research Priorities Use Cases

What characteristics predict response to pelvic floor muscle training (PFMT) in women with Stress Urinary Incontinence (SUI)?

PFMT, or “Kegels,” are the first-line treatment for women with SUI, but they are inconsistently effective. Study will identify determinants of success with PFMT in a prospective subcohort of women aged 18+ with SUI. Hypothesized moderators of PFMT outcome spanning the medical and social ecological model (e.g., self-efficacy, BMI, physical activity, race, occupation, socioeconomic status, education, PFM strength) will ...more »

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3 votes
Ideate
(@diane.newman)

AoU Research Priorities Use Cases

What characteristics predict response to pelvic floor muscle training (PFMT) in women with Stress Urinary Incontinence (SUI)?

PFMT, or “Kegels,” are the first-line treatment for women with SUI, but they are inconsistently effective. Study will identify determinants of success with PFMT in a prospective subcohort of women aged 18+ with SUI. Hypothesized moderators of PFMT outcome spanning the medical and social ecological model (e.g., self-efficacy, BMI, physical activity, race, occupation, socioeconomic status, education, PFM strength) will ...more »

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3 votes
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(@noemie.elhadad)

AoU Research Priorities Use Cases

What are the genetic, epigenetic, and environmental factors of endometriosis, and how can they help us identify its subtypes?

Endometriosis is a systemic condition with a heavy burden on patients. It is estimated that 10% of women in reproductive age have endometriosis, but its etiology is still unknown. While it is accepted that endometriosis is a heterogeneous condition, what the exact subtypes of the disease are is still an open question.

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144 votes
Ideate
(@girlwithaclue)

AoU Research Priorities Use Cases

What is the relationship between pregnancy-childbirth-and post-partum immune system functioning and autoimmune disorders?

Goals: To determine if women are more susceptible to infections and autoimmune diseases around the period of childbirth. To determine if infectious diseases like Lyme Disease are a precipitating factor for other diseases like scleroderma. Participants: Females of childbearing age Data: Genetic, Environmental, Lab work, Pain assessments, Any factors that could moderate outcomes. Frequency of data: monthly ? during pregnancy ...more »

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11 votes
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