Showing 3 ideas for tag "allergy"
(@jpcastner15) kudos icon +

AoU Research Priorities Use Cases

What are the multi-level, immune-mediated, environmental exposure endotype pathways of environmental illness? Asthma/allergies?

Focusing recruitment on communities with a disproportionate burden of environmental exposure (such as Western New York), develop and test a multi-level model to ascertain the burden of environmental illness symptom clusters, asthma, and allergies attributable to environmental factors at the 1) community/neighborhood, 2) household, 3) personal, 4) internal body burden 5) inflammatory biomarker response levels over time.... more »

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(@kochspostulate) kudos icon +

AoU Research Priorities Use Cases

Can allergies predict the development of autoimmune or inflammatory disease? Does treatment reduce the risk?

Identify a group of participants with environmental/food allergies and ask if the allergies are well controlled. Use observational data over many years to determine the relative rate of development of autoimmune/inflammatory illness in participants whose allergies are/are not well controlled.

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(@klosecall) kudos icon +

AoU Research Priorities Use Cases

Can pollen allergies be isolated by genetics, confirmed by allergy testing, and exposure be tracked to limit asthma attacks?

A cohort of asthma patients (who believe they have a pollen allergy) would undergo genetic testing to identify genetic markers. Those patients would undergo blood and skin allergy testing to confirm the allergy, and then the patients would be utilize a mobile monitor to track the weather and environmental exposures (esp. pollen) that are causal to asthma incidences. With a more complete picture of pollen allergen impacts... more »

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