(@srileka.mylvaganam)

AoU Research Priorities Use Cases

Can foot amputation be prevented in diabetics with AI powered diagnosis?

Foot amputation is a major problem in diabetics in the south Asia. A small blister or ulcer in the foot can develop into a major complication where the foot/toe needs to be amputated. Due to lack of sensation in the foot, most of the time the injuries are unnoticed. An AI powered solution that involves sensors and certain preliminary tests to prematurely detect the risk of foot amputation in diabetics at an earlier stage... more »

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(@aawc2018)

AoU Research Priorities Use Cases

Analysis of the impact of payer on the outcome of patients with leg ulcers (including amputations) and race related differences

US Wound Registry data confirm outcome of African Americans with lower extremity wounds is worse than in whites, particularly true for DFU outcomes where amputation rates are higher. USWR data confirm use of advanced therapeutics in wound care is determined by payer. Whether a Medicare beneficiary has a secondary insurance determines if they get a cellular product, & use of all advanced therapeutics has changed with rise... more »

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(@tlzjones)

AoU Research Priorities Use Cases

Do specific diabetes drugs increase the risk of peripheral artery disease, a diabetic foot ulcer or an amputation?

A major advance in diabetes treatment is the finding that specific glucose-lowering drugs reduce the risk of cardiovascular disease. The results were tempered by the increased risk of amputations for the groups that received the SGLT2 inhibitor, canagliflozin. The generalizability of this finding is unknown. An understanding of the association of specific diabetes drugs with lower extremity complications will allow... more »

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(@tlzjones)

AoU Research Priorities Use Cases

Do specific diabetes drugs increase the risk of peripheral artery disease, a diabetic foot ulcer or an amputation?

A major advance in diabetes treatment is the finding that specific glucose-lowering drugs reduce the risk of cardiovascular disease. The results were tempered by the increased risk of amputations for the groups that received the SGLT2 inhibitor, canagliflozin. The generalizability of this finding is unknown. An understanding of the association of specific diabetes drugs with lower extremity complications will allow... more »

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10 votes
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(@alison.cernich)

AoU Research Priorities Use Cases

What are the characteristics of people who sustain traumatic injury who have optimal recovery versus those who do not?

Injury to the musculoskeletal system, the central and peripheral nervous system, or other conditions that cause disability are associated with significant morbidity. These injuries have substantial economic cost due to inability to work, high health care costs, and the need for long-term rehabilitation. Bioarkers of plasticity and contextual factors may predict functional outcome and guide prescription of the intensity... more »

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20 votes
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