(@mara.mather)

AoU Research Priorities Use Cases

What health factors relate to positive and negative emotional bias?

When two faces are presented simultaneously, depressed people show a bias to look at the face with a negative expression. In contrast, older adults tend to look away from faces with negative expressions, consistent with the positivity effect seen in healthy older adults and their generally reduced negative affect. Little is known about how health helps shape these emotional biases. We also don't know how these biases... more »

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14 votes
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(@mara.mather)

AoU Research Priorities Use Cases

What health factors relate to positive and negative emotional bias?

When two faces are presented simultaneously, depressed people show a bias to look at the face with a negative expression. In contrast, older adults tend to look away from faces with negative expressions, consistent with the positivity effect seen in healthy older adults and their generally reduced negative affect. Little is known about how health helps shape these emotional biases. We also don't know how these biases... more »

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14 votes
Ideate
(@alan.sanders.md)

AoU Research Priorities Use Cases

Which genetic and environmental factors contribute to sexual orientation, and related health conditions?

Gays, lesbians, and bisexuals are underrepresented in biomedical research. While much relevant data is already planned for collection by AllofUs, additional or elaborated measures (see "data items") would help in seeking new leads and advancing work on pre-existing questions in the field. These items include sociodemographic (e.g., trait information), clinical (various associated conditions), and biological (genomic,... more »

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30 votes
Ideate
(@drirene)

AoU Research Priorities Use Cases

Could the Precision Medicine Initiative Reduce Social Inequality?

The proposed study would identify microbial communities and metabolic profiles associated with stigmatized conditions such as idiopathic malodor or mental health. Working with systemic malodor/PATM community provides unprecedented opportunities to explore biomarkers of depression, social stress, diabetes, inflammatory diseases, dental, cardiovascular, and digestive health, exposure to antibiotics, lifestyle & dietary... more »

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219 votes
Ideate
(@sunshi17)

AoU Research Priorities Use Cases

Does pregnancy loss lead to increase risk for anxiety and pregnancy during subsequent pregnancies and deliveries

Follow women with pregnancy loss and screen for anxiety and depression during and after (each) pregnancy. Have a control group that has not experienced pregnancy loss and screen for anxiety and depression during and after (each) pregnancy. I would use separate instruments to screen for anxiety and depression.

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8 votes
Ideate