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AoU Research Priorities Use Cases

What are the genetic and environmental risk factors that contribute to the broader autism phenotype in adolescents and adults?

To study genotype-phenotype correlations, utilize measures targeting the Broader Autism Phenotype: social and communication scales (SRS), Connors Rating Scale for ADHD, ratings of depressive symptoms (PHQ-9), anxiety disorders, & adverse childhood experiences (ACEs) & traumatic life events. Children transitioning to adulthood during the study will have repeat assessment of function and mental health status at a later ...more »

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AoU Research Priorities Use Cases

What are the genetic and environmental risk factors that contribute to the broader autism phenotype in adolescents and adults?

To study genotype-phenotype correlations, utilize measures targeting the Broader Autism Phenotype: social and communication scales (SRS), Connors Rating Scale for ADHD, ratings of depressive symptoms (PHQ-9), anxiety disorders, & adverse childhood experiences (ACEs) & traumatic life events. Children transitioning to adulthood during the study will have repeat assessment of function and mental health status at a later ...more »

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42 votes
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(@nichd.allofus)

AoU Research Priorities Use Cases

What is the genetic architecture of neurodevelopmental problems and how does it relate to health disparities?

From a diverse sample of children in both clinical and non-clinical settings, investigate genetic contributions to a wide range of neurodevelopmental problems (NPs). Individual-variant and polygenic approaches can advance our understanding of the genetic overlap between, and specificity in, different types of NPs. In a large and diverse sample that includes different racial/ethnic and socioeconomic groups, these techniques ...more »

Voting

33 votes
Ideate
(@nichd.allofus)

AoU Research Priorities Use Cases

What is the genetic architecture of neurodevelopmental problems and how does it relate to health disparities?

From a diverse sample of children in both clinical and non-clinical settings, investigate genetic contributions to a wide range of neurodevelopmental problems (NPs). Individual-variant and polygenic approaches can advance our understanding of the genetic overlap between, and specificity in, different types of NPs. In a large and diverse sample that includes different racial/ethnic and socioeconomic groups, these techniques ...more »

Voting

33 votes
Ideate