(@mara.mather)

AoU Research Priorities Use Cases

What health factors relate to positive and negative emotional bias?

When two faces are presented simultaneously, depressed people show a bias to look at the face with a negative expression. In contrast, older adults tend to look away from faces with negative expressions, consistent with the positivity effect seen in healthy older adults and their generally reduced negative affect. Little is known about how health helps shape these emotional biases. We also don't know how these biases ...more »

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(@nichd.allofus)

AoU Research Priorities Use Cases

How do genetic factors of ADHD influence treatment strategies? Can they affect success of treatment or the choice of therapy?

Screen school-age children for ADHD by testing, if feasible, or by electronic health record search. Perform WGS on children as the preferred strategy to identify new genetic associations and confirm previously reported genetic associations. If WGS is not possible, develop a marker panel and test children who have ADHD for known or suspected genetic factors. Follow children by periodic medical evaluations and school performance ...more »

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